Pall Filters Frequently Asked Questions 

Sets with
PALL® filters
are coming!

Select Sapphire administration sets have integrated filters manufactured by Pall Medical. Filters are available in different pore sizes that enable retention of particles, bacteria, and fungi as well as eliminate air.

Here are some commonly asked
questions & answers about filters:

The filter contains an air vent and membranes. Fluid enters via the inlet through the vented component, and then passes through the filter. When primed correctly, the membrane will become wet and will not permit air to pass forward towards the patient.


1.2 and 0.2 micron filter options are available.

Pall has conducted membrane binding studies. The membrane, which services as the filtering mechanism of the filter has been shown to be low drug binding.

Yes. Hydrophilic membrane material is polyethersulfone (PES), which is considered low protein binding.

Prior to use:

  • Always read and follow instructions in the user manual.
  • Close at least one clamp on the administration set.
  • Remove protective cover and insert spike into solution container.



  1. Verify the administration set is disconnected from the catheter/access site.
  2. Open all clamps of the administration set and make sure there are no other occlusions blocking the set.
  3. Hold the Pall filter so that the arrow side of the filter is pointing upwards (please download the PDF for full instructions with images). 
  4. Allow the medication to prime the filter, wetting the filter membrane and eliminating air. Once all air has been removed and fluid is observed at the end of the set, priming is complete.
  5. If after priming, a patient is not connected to the administration set, close the clamp below the filter until the patient is connected.
  • Ensure administration set’s end cap is secure.
  • Close clamp below filter.
  • This can be caused by not closing the clamp below the filter.
  • Placing the filter at a higher level than the patient during the infusion can result in prime loss, while lowering it below the patient can cause back-siphoning or blood backing up. To prevent this, it is important to always maintain the position of a properly primed filter at or below the level of the patient.

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